Failure of cimetidine and etidronate disodium to suppress parathyroid hormone level and hypercalcemia in primary hyperparathyroidism.
نویسندگان
چکیده
منابع مشابه
Parathyroid hormone-related peptide and primary hyperparathyroidism.
The parathyroid hormone-related peptide (PTHrP) has been shown to be the major pathogenic factor to humoral hypercalcemia of malignancy (HHM). The presence of PTHrP in many normal tissues and in normal or abnormal parathyroids has been described in literature and its role has been investigated. PTHrP release from parathyroid cells into the extracellular space has been demonstrated to depend on ...
متن کاملHypercalcemia in a patient with primary hyperparathyroidism and acromegaly: distinct roles of growth hormone and parathyroid hormone in the development of hypercalcemia.
We herein report a case of primary hyperparathyroidism associated with acromegaly. Although serum parathyroid hormone (PTH) levels increased after the resection of a pituitary adenoma, levels of serum 1a, 25-dihydroxyvitamin D [1, 25(OH)2D] decreased but remained above the normal upper limit. After resection of a parathyroid adenoma, serum PTH, 1, 25(OH)2D, calcium (Ca), and phosphate were all ...
متن کاملIntraoperative parathyroid hormone monitoring in neonatal severe primary hyperparathyroidism.
Neonatal severe primary hyperparathyroidism presents in the first days of life with severe life-threatening hypercalcemia. It is associated with an inactivating homozygous mutation of the calcium sensing receptor gene. Total parathyroidectomy is the treatment of choice, so the surgeon must identify all the parathyroid tissue, including supernumerary and ectopic glands. We present the case of an...
متن کاملClinical usefulness of intraoperative parathyroid hormone monitoring for primary hyperparathyroidism
Purpose The availability of intraoperative parathyroid hormone (IOPTH) monitoring allows successful focused parathyroidectomy for primary hyperparathyroidism (pHPT). The objective of this study was to report our initial experience in IOPTH monitoring during parathyroid surgery for primary hyperparathyroidsim. Methods Between May 2011 and February 2013, 37 patients underwent focused parathyroi...
متن کاملPersistent parathyroid hormone elevation following curative parathyroidectomy for primary hyperparathyroidism.
BACKGROUND Persistent elevation of parathyroid hormone (PTH) levels following parathyroidectomy may indicate residual abnormal parathyroid tissue. OBJECTIVE To determine the clinical significance and risk factors for persistent PTH elevation following curative parathyroidectomy. METHODS A prospective study of consecutive patients with primary hyperparathyroidism who had resolution of hyperc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 1988
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.77.113